
James Young Simpson
Full Calendar
THIS MONTH IN ANESTHESIA HISTORY: NOVEMBER
1793 November 28: Antoine Lavoisier surrenders to French revolutionary government. He is imprisoned and executed by
guillotine in 1794.
1815 November 1::Crawford W. Long is born in
Danielsville
,
Georgia
. On the afternoon of March
30, 1842, in
Jefferson
,
Georgia
, Dr. Long removed a small
tumor from the neck of James Venable while the patient remained calm after
breathing ether vapor. Thus Long performed the first
surgical operation under ether anesthesia. Long continued to use ether in
several other operations, but failed to report his achievement until after
William Morton's public demonstration of ether anesthesia in October, 1846.

Crawford W. Long, M.D.
1821 November 9: French writer Charles Baudelaire is born
in
Paris
. Although probably best known for his poetry collection
_Les Fleurs du mal_
[_Flowers of Evil_, first edition 1857], Baudelaire was also a literary and art
critic and beginning in 1848 translated many works of Poe into French. His own
dark poetry, often fueled by sessions of hashish smoking, was very
controversial during his lifetime. In his essay "Poem of Hashish" [1895], he
made some interesting observations about anesthesia: "Despite the
admirable services which ether and chloroform have rendered to humanity, it
seems to me that from the point of view of the idealist philosophy the same
moral stigma is branded on all modern inventions which tend to diminish human
free will and necessary pain. It was not without a certain admiration that I
once listened to the paradox of an officer who told me of the cruel operation
undergone by a French general at El-Aghouat, and of
which, despite chloroform, he died. This general was a very brave man, and even
something more: one of those souls to which one naturally applies the term chivalrous.
It was not, he said to me, chloroform that he needed, but the eyes of all the
army and the music of its bands. That might have saved him. The surgeon did not
agree with the officer, but the chaplain would doubtless have admired these
sentiments." Baudelaire died in
Paris
from the ravages of syphilis on August
31, 1867, at age 46.

Charles Baudelaire
[1821-1867]
1832 November 26:
American author Louisa May Alcott is born in
Germantown
,
now a part of
Philadelphia
,
Pennsylvania
. She is perhaps best
known for her novels Little Women and
its sequel, Little Men [1871].
However, she also published several successful thrillers under the pseudonym
A.B. Barnard. Alcott worked as a nurse for six weeks at a Union hospital in
Washington, D.C., during the Civil War, and her first significant work, Hospital Sketches [1863] resulted from
that experience. This work includes descriptions of the brutal treatment of the
wounded soldiers of that time; Alcott observes that "the merciful magic of
ether" was not always used in surgery. After contracting typhoid pneumonia
during this period, Alcott was treated with large doses of calomel, a compound
containing mercury. For the rest of her life, until her death on March 6, 1888,
the long-term side effects led her to self-medicate with opium and morphine.
Opium addiction is explored in some of her later writings, such as The Marble Woman; or, The Mysterious Model.
Louisa May Alcott
[1832-1888]
1846 November 7: Surgeon George Hayward performed a leg amputation and a lower jaw
removal under ether anesthesia at the
Massachusetts General
Hospital
.
These surgeries were the third and fourth at which
Boston
dentist William Thomas Green Morton
served as anesthetist.
1846 November 9: Henry J. Bigelow, junior surgeon at the
Massachusetts General Hospital, reported on Morton's four successful ether anesthesias to a meeting of the Boston Society for Medical
Improvements.
1846 November 12: Letter patent no. 4848 issued to Charles T. Jackson
and William T.G. Morton for 10% of all profits on the use of ether in surgical
operations. Because of vociferous opposition from the medical and dental
communities to such a patent, Jackson and Morton quickly made their discovery
known and freely available.
1846 November 12: First surgery in private practice under
ether anesthesia in
Boston
takes place. J. Mason Warren, son of John Collins Warren, is the surgeon.
1846 November 18: Bigelow's account is published in the Boston Medical and Surgical Journal, launching the spread of ether anesthesia around the
world.
1846 November 21: In a letter to William T.G. Morton, Oliver Wendell
Holmes, Sr., suggests the word "anaesthesia"
to describe the mental state produced by the inhalation of ether vapor.

Oliver Wendell Holmes, Sr. [1809-1894]
1847 November 8: In
Edinburgh
,
Scotland
, James
Young Simpson introduced chloroform into clinical practice. The patient was
Wilhelmina Carstairs, daughter of a physician.
1856 November 10: At London's King's College Hospital, John Snow makes the first clinical
administration of amylene, a gas he had extensively
investigated in animals. By July, 1857, Snow abandons use of the gas after two
of his patients die. In the
summer of 1857 a
New York
physician, John G. Orton, published two accounts in the Boston Medical and
Surgical Journal of his use of amylene in a
toenail extraction and an obstetric case. Dr. Orton noted that he had obtained
the amylene from John Snow. There is a fascinating
footnote to the amylene story. In a March 2, 1857,
letter, the
Paris
correspondent of the New York Times reported excitedly on an operation
with amylene "for necrosis of the tibia"
that he had witnessed. The reporter noted of the patient, "She did not go
to sleep, and yet she felt no pain; her eyes remained open during the whole
operation, which lasted nearly an hour...." A purified form of amylene, pental (trimethyl ethylene), gained some popularity in
Germany
and the
United Kingdom
until the end of the
century. More about amylene can be found at http://www.anes.uab.edu/aneshist/amylene.htm
1868 November: Dr. Edmund Andrews publishes in the Chicago Medical Examiner a
paper proposing administration of nitrous oxide with oxygen in a premixed
combination of 80 to 20 percent.
1879 November 4: American humorist and author Will Rogers is born in
Indian Territory [what is now
Oklahoma
].
Rogers
had a
long career on stage, radio and in films; he also wrote some 4,000 syndicated
newspaper columns and six books. He was especially known for his political
humor. Among his books is Ether & Me...or Just
Relax [1937, reprinted in 1973], a humorous account of a visit to the
dentist. Along with famed pilot Wiley Post,
Rogers
died in a plane crash near Point Barrow,
Alaska
,
on August 15, 1935. Learn more about
Rogers
at http://www.cmgww.com/historic/rogers/index.php
1883 November 13: James Marion Sims, a surgeon famous for his vesicovaginal operation, dies. After Morton's October,
1846, public demonstration of ether anesthesia in
Boston
,
Sims urged
Georgia
physician Crawford Long to publish an account of operations using ether that
Long had performed in 1842. Long's account finally
appeared in the December 1849, issue of the Southern Medical and Surgical
Journal. Sims was born on January 21, 1813, in
South
Carolina
and received his M.D. from
Jefferson
Medical
College
in
Philadelphia
in 1835. For some years he practiced in
Montgomery
,
Alabama
, but in 1853 moved to
New York
where two years
later he opened the world's first hospital for women. He served a term as
President of the American Medical Association in 1876-77.

James Marion Sims, M.D.
[1813-1883]
1884 November 15: Vassily von Anrep publishes first extensive account of clinical use of
cocaine in a Russian journal.
1894 November 30: Ernst Amory Codman [1869-1940] and Harvey Cushing
introduced the anesthetic record on or before this date.
1905 November 5: Actor Joel McCrea is born. In addition to
numerous other roles, McCrea starred as William T.G. Morton in The Great
Moment [1944], a film biography directed by
Preston
Sturges.
2001 November 9: The second annual National Anaesthesia Day is held in
Great
Britain
under the auspices of the
Royal
College
of Anaesthetists. The first celebration was held May
25, 2000.
2005 November 5: British novelist John Fowles dies at the age of 79. Well-known for such later
novels as The Magus and The French Lieutenant's Woman, Fowles achieved critical and commercial success early with
his first novel, The Collector [1963]. That novel tells the story of Frederick
Clegg, a meek clerk and butterfly collector who decides to elevate his
collecting and kidnaps beautiful art student Miranda Grey as she is walking
home from class. Clegg uses a rag soaked in chloroform to subdue her. A film
version of the novel appeared in 1965 and featured Terence Stamp as Clegg and
Samantha Eggar as Grey. Both novel and film have
extended scenes of the criminal use of chloroform. Fowles was born in Leigh-on-Sea,
Essex
,
England
, on
March 31, 1926. [For more information on such real-life uses of
chloroform, see Payne JP. The criminal use of chloroform. Anaesthesia. 1998 Jul;53(7):685-90]