Back to Lab Research
Robert A. Pearce, MD, PhD
Professor and Chair of Anesthesiology
Department of Anesthesiology
University of Wisconsin
Research in the Pearce laboratory is focused on the mechanisms by which general anesthetics alter brain function. We are particularly interested in understanding how modulation of GABAA receptors impairs memory – a fundamental endpoint of anesthesia. For our studies we utilize expressed recombinant receptors and hippocampal brain slices to investigate the roles of specific subunit combinations and cell types in the control of learning and memory.